蔡进辉个人简介
基本信息
姓名:蔡进辉
出生年月:1992.10
学位:博士
职称:校聘教授
研究领域(方向):(1)不对称催化; (2)绿色有机合成催化; (3)自由基化学 (4)杂环化合物的合成方法学及其在药物治疗上的应用研究。
联系方式:
邮箱:jinhuicai@usc.edu.cn;15898595191@163.com
个人简介
蔡进辉,男,1992年生,湖南益阳人,博士,校聘教授,硕士生导师。现主持湖南省自然科学青年基金、bv伟德国际体育官网博士科研启动基金等,参与多项青年基金项目、面上项目等;目前在Chem、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、ACS Catalysis、Chem Catalysis、Org. Lett.、Green Chem.、Adv. Syn. Catal.、J. Org. Chem.、Org. Biomol. Chem.、Asian. J. Org. Chem.、Synthesis、RSC Adv.等期刊上发表论文19篇,其中以第一作者以及导师第一本人第二发表论文13篇;授权专利2项。
教育经历
2017/09-2020/06 武汉大学,化学与分子科学学院,博士,导师:刘文博
2014/09-2017/06 湘潭大学,化学学院,硕士,导师:邓国军、黄华文
2013/09-2014/05 中科院化学所,分子识别与功能实验室,联培本科生,导师:王从洋
2010/09-2014/06 湘潭大学,化学学院,学士
科研、学术与访学工作经历
1. 2021/06-现今,bv伟德国际体育官网,伟德betvlctor体育,校聘教授
2. 2020/07-2021/06,浙江大学,化学系,博士后
主持或参加科研项目(课题)情况
2022.01—2024.12 基于钴催化1,6-烯炔化合物和腈类化合物的不对称环化反应的研究,湖南省自然科学基金(2022JJ40353),主持,经费5万元;
2021.06—至今 廉价金属钴催化1,6-烯炔化合物的不对称碳环化反应的研究,bv伟德国际体育官网博士启动经费,主持,经费30万元。
主要论文:
1. Dahan Wang*, Xiaoyuan Wan, Yazheng Zhou, Jinbing Liu, Jinhui Cai*, Guo-Jun Deng*, Facile Synthesis of Fully Substituted 1,2,4-Triazoles via [3+2] Cycloaddition of Nitrileimines with Amidine under Transition Metal-Free Conditions. Asian J. Org. Chem. 2023, 12, e202200674. (中科院三区,IF= 3.12 )
2. Jinhui Cai*, Kaili Cen, Wangzhen Shen, Li-Gang Bai, Wen-Bo Liu,* [2+2+2] Cycloaddition of nitriles to enantioenriched and highly substituted pyridines. Chem Catal. 2022, 2, 2889.
3. Kaili Cen#, Muhammad Usman#, Wangzhen Shen, Meijing Liu, Rong Yang, Jinhui Cai,* A review for the assembly of multi-substituted pyridines via Co-catalyzed [2+2+2] cycloaddition with nitriles. Org. Biomol. Chem. 2022, 20, 7391 − 7404. (中科院三区,IF= 3.89 )
4. Jinhui Cai#, Li-Gang Bai#, Yiliang Zhang, Zhen-Kai Wang, Fei Yao, Jin-Huang Peng, Wei Yan, Yan Wang, Chao Zheng, Wen-Bo Liu, Nickel-Catalyzed Enantioselective [2+2+2] Cycloaddition of Malononitriles and Alkynes. Chem, 2021, 7, 799 – 811. (中科院一区TOP,IF= 25.83, 共一)
5. Huawen Huang*, Jinhui Cai, Xiaochen Ji, Fuhong Xiao, Ya Chen, Guo-Jun Deng*, Internal Oxidant-Triggered Aerobic Oxygenation and Cyclization of Indoles under Copper Catalysis. Angew. Chem. Int. Ed. 2016, 55, 307 − 311. (中科院一区TOP,IF= 16.82, 导师第一,本人第二)
6. Qiang Wei#, Jinhui Cai #, Xu-Dong Hu, Jing Zhao, Hengjiang Cong, Chao Zheng, and Wen-Bo Liu, Enantioselective Access to γ-All-Carbon Quaternary Center-Containing Cyclohexnaones by Palladium-Catalyzed Desymmetrization. ACS Catal. 2020, 10, 216 – 224. (中科院一区TOP,IF= 13.7, 共一)
7. Jinhui Cai#, Feifei Li#, Guo-Jun Deng, Xiaochen Ji*, Huawen Huang*, The Cyclopropylimine Rearrangement/Povarov Reaction Cascade for the Assembly of Pyrrolo[3,2-c]quinoline Derivatives. Green Chem. 2016, 18, 3503 – 3506. (中科院一区,IF= 11.03, 共一)
8. Jinhui Cai, Zhen-Kai Wang, Yun-Hao Zhang, Fei Yao, Xu-Dong Hu, and Wen-Bo Liu, Synthesis of Polysubstituted 2-Naphthols by Palladium-Catalyzed Intramolecular Arylation/Aromatization Cascade. Adv. Synth. Catal. 2020, 362, 1303 – 1308. (中科院二区,IF= 5.98)
9. Jinhui Cai, Zhen-Kai Wang, Muhammad Usman, Zhi-Wu Lu, Xu-Dong Hu, and Wen-Bo Liu, Enantioselective Synthesis of βQuaternary Carbon-Containing Chromanes and 3,4-Dihydropyrans via Cu-Catalyzed Intramolecular C−O Bond Formation. Org. Lett. 2019, 21, 8852 – 8856. (中科院一区,IF= 6.07)
10. Jinhui Cai, Qiang Wei, Xu-Dong Hu, Yan Zhang, Weishuang Li, Hengjiang Cong, Wei Liu, Wen-Bo Liu, Enantioselective Construction of Bridgehead Quaternary Carbon Containing Bicyclo[3.3.1]nonanes by Palladium-Catalyzed Desymmetric Arylation. Synthesis 2018, 50, 1661 – 1666. (中科院三区,IF= 2.97)
11. Yujia Xia#, Jinhui Cai #, Huawen Huang* and Guo-Jun Deng*, Synthesis of polysubstituted pyridines from oxime acetates using NH4I as a dual-function promoter. Org. Biomol. Chem. 2018, 16, 124 − 129. (中科院三区,IF= 3.89,共一)
12. Huawen Huang*, Jinhui Cai, Hao Xie, Jing Tan, Feifei Li, and Guo-Jun Deng*, Transition-Metal-Free N−O Reduction of Oximes: A Modular Synthesis of Fluorinated Pyridines. Org. Lett. 2017, 19, 3743 − 3746. (中科院一区,IF= 6.07,导师第一,本人第二)
13. Huawen Huang*, Jinhui Cai, Lichang Tang, Zilong Wang, Feifei Li, Gu-Jun Deng*, Metal-Free Assembly of Polysubstituted Pyridines from Oximes and Acroleins. J. Org. Chem. 2016, 81, 1499 − 1505. (中科院二区,IF= 4.20,导师第一,本人第二)
14. Huawen Huang*, Jinhui Cai, Guo-Jun Deng*, O-Acyl Oximes: Versatile Building Blocks for N-heterocycle Formation in Recent Transition Metal Catalysis, Org. Biomol. Chem. 2016, 14, 1519 − 1530. (中科院三区,IF= 3.89,导师第一,本人第二) (ESI高被引论文)
15. Zhi-Wu Lu#, Xu-Dong Hu#, Hui Zhang, Xiao-Wen Zhang, Jinhui Cai, Muhammad Usman, Hengjiang Cong, Wen-Bo Liu, Enantioselective Assembly of Cycloenones with a Nitrile-Containing All-Carbon Quaternary Center from Malononitriles Enabled by Ni-Catalysis. J. Am. Chem. Soc. 2020, 142, 7328 – 7333. (中科院一区TOP,IF= 16.38)
16. Huawen Huang,* Feifei Li, Zhenhua Xu, Jinhui Cai, Xiaochen Ji,* and Guo-Jun Deng, Base‐Promoted [3+2]‐Annulation of Oxime Esters and Aldehydes for Rapid Isoxazoline Formation. Adv. Synth. Catal. 2017, 359, 3102 – 3107. (中科院二区,IF= 5.98)
17. Hao Xie, Jinhui Cai, Zilong Wang, Huawen Huang*, Guo-Jun Deng*, A Three-component Approach to 3,5-Diaryl-1,2,4-thiadiazoles under Transition-Metal-Free Conditions. Org. Lett. 2016, 18, 2196 – 2199. (中科院一区,IF= 6.07)
18. Huamin Wang, Jinhui Cai, Huawen Huang, Guo-Jun Deng*, Palladium-catalyzed Phtha
-lazinone Synthesis Using Paraformaldehyde as Carbon Source. Org. Lett. 2014, 16, 5324 – 5327. (中科院一区,IF= 6.07)
19. Huawen Huang,* Lichang Tang, Jinhui Cai, and Guo-Jun Deng,* Mild and ambient annulations for pyrrole synthesis from amines and arylacetaldehydes. RSC Adv. 2016, 6, 7011 – 7014. (中科院四区,IF= 4.04)
专利:
1. 刘文博,蔡进辉,一种季碳中心的全取代吡啶化合物及其制备方法,中国专利,专利号:ZL202010507993.7。
2. 黄华文,蔡进辉,谢艳军,邓国军,2,3a-二取代-3H–吡唑并[1,5-a]吲哚-4(3a
H)-酮、衍生物及其合成方法,中国专利,专利号:ZL201510675567.3。
二、出版的著作(教材)及获奖
无